ANA (Antinuclear Antibody)
Screening test for autoimmune diseases. Positive in lupus, Sjögren's, scleroderma, and others. Titer and pattern guide further testing.
Test Information
Reports In
Same day (6 hours)
Parameters
1
Requisites
Blood Sample
Sample Type
Blood
Measures
Antibodies against nuclear antigens
Identifies
SLE, Sjögren's, scleroderma, myositis, mixed connective tissue disease; screening for autoimmune disorders
What is the ANA Test?
ANA (Antinuclear Antibody) test detects antibodies that attack your own cell nuclei. A positive ANA suggests an autoimmune process — the body's immune system attacking itself. While most commonly associated with Lupus (SLE), ANA can be positive in many autoimmune diseases and even in some healthy people.
Why Should You Take This Test?
ANA is sensitive for lupus—95%+ of SLE patients are positive. Low titer (1:40) can be normal; high titer with symptoms warrants workup.
Who Should Get Tested?
Suspected Lupus (SLE)
ANA is positive in >95% of lupus patients.
Unexplained Joint Pain + Rash
Classic lupus presentation.
Multiple System Involvement
Skin, joints, kidneys, blood — autoimmune pattern.
Warning Signs — When Should You Get This Test?
Common Conditions Detected
Frequently Booked Together
Tests commonly ordered alongside ANA for a complete picture
dsDNA Antibodies
Specific for lupus if ANA is positive
Complement (C3, C4)
Low complement suggests active autoimmune disease
CBC & RFT
Assess organ involvement
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